The adequacy of resection margin for non-infiltrative soft-tissue sarcomas

AbstractObjectives There remains no consensus on what constitutes an adequate margin of resection for non-infiltrative soft-tissue sarcomas (STSs). We aimed to investigate the role margins in millimetres STSs. Methods 502 patients who underwent surgical a localized, non-infiltrative, high-grade STSs were studied. The prognostic significance width was analysed and compared with conventional R- R+1-classification margins. Results overall local recurrence (LR) rate 13%; 9% 27% negative positive margins, respectively (p < 0.001). In LR rates greater than 10% ≤5.0 mm but reduced less 4% >5.0 mm. When classified by (or R+1)-classification, 5-year cumulative incidence 8%, 23% (16%), 31% R0, R1, R2, respectively, which did not stratify risk On other hand, accurate stratification possible metric distance; 29%, 10%, 1% 0 mm, 0.1–5.0 This classification also stratified or without adjuvant radiotherapy. Conclusion While is essential optimize control STSs, 5 minimises failure regardless use